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CD321 (JAM-1) Mouse, anti-Human, R718, Clone: M.AB.F11, BD OptiBuild™

Catalog No. BDB752289 Shop All BD Biosciences Products
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BDB752289 50 μg
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Catalog No. BDB752289 Supplier BD Biosciences Supplier No. 752289
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Description

Mouse Monoclonal Antibody

The M.Ab.F11 monoclonal antibody specifically binds to CD321 which is also known as JAM-1 (Junctional adhesion molecule 1), Junctional adhesion molecule A (JAM-A), and F11 Receptor (F11R). CD321 is a 32-35 kDa type I transmembrane glycoprotein that includes two extracellular immunoglobulin-like domains. CD321 is expressed on platelets, leucocytes, red blood cells, endothelial cells, epithelial cells, and various cell lines. CD321 functions as an adhesion receptor molecule on platelets. It also supports the tight junction formation between endothelial cells, where it may regulate the transendothelial migration of leucocytes, and epithelial cells. M.Ab.F11 is a stimulatory antibody that can induce morphological changes, granule secretion, and aggregation in human platelets.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD321 (JAM-1)
Applications Flow Cytometry
Classification Monoclonal
Clone M.AB.F11
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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