Invitrogen™ CD323 (JAM3) Monoclonal Antibody (CRAM-18 F26)

Catalog No.	Quantity
PIMA528231	1 mg

Catalog No. PIMA528231 Supplier Invitrogen™ Supplier No. MA528231

Description

Rat Monoclonal Antibody

Rat anti Mouse JAM-c antibody, clone CRAM-18 F26 recognizes mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.

JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

Specifications

• Antigen: CD323 (JAM3)
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunocytochemistry
• Classification: Monoclonal
• Clone: CRAM-18 F26
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: JAM3
• Gene Accession No.: Q9D8B7
• Gene Alias: 1110002N23Rik; JAM-2; JAM3; JAM-3; JAMC; JAM-C; Jcam3; junction adhesion molecule 3; junction cell adhesion molecule 3; junction cell adhesion molecule C; junctional adhesion molecule 3; Junctional adhesion molecule C; sJAM-C; Soluble form of JAM-C; UNQ859/PRO1868
• Gene Symbols: JAM3
• Host Species: Rat
• Immunogen: Recombinant soluble JAM-C.
• Purification Method: Protein G
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 83964
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a