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CD33 Mouse, anti-Human, R718, Clone: WM53, BD Horizon™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 566971
Description
The WM53 monoclonal antibody specifically recognizes CD33 which is also known as Sialic acid-binding Ig-like lectin 3 (Siglec-3) or gp67. CD33 is a 67 kDa type I transmembrane glycoprotein that is variably expressed on myeloid progenitors, monocytes, macrophages, dendritic cells, neutrophils, basophils, mast cells, and on some activated T cells and NK cells. Normal lymphocytes, platelets, erythrocytes and pluripotent hematopoietic stem cells do not express the CD33 antigen. This glycoprotein reportedly functions as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.
Specifications
| CD33 | |
| Monoclonal | |
| R718 | |
| 100 Tests | |
| Primary | |
| Refrigerate Upon Arrival |
| Flow Cytometry | |
| WM53 | |
| Mouse | |
| RUO | |
| Human | |
| Liquid |
Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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