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CD33 Mouse, anti-Human, R718, Clone: WM53, BD Horizon™

Catalog No. BDB566972 Shop All BD Biosciences Products
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Catalog No. BDB566972 Supplier BD Biosciences Supplier No. 566972
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Mouse Monoclonal Antibody

The WM53 monoclonal antibody specifically recognizes CD33 which is also known as Sialic acid-binding Ig-like lectin 3 (Siglec-3) or gp67. CD33 is a 67 kDa type I transmembrane glycoprotein that is variably expressed on myeloid progenitors, monocytes, macrophages, dendritic cells, neutrophils, basophils, mast cells, and on some activated T cells and NK cells. Normal lymphocytes, platelets, erythrocytes and pluripotent hematopoietic stem cells do not express the CD33 antigen. This glycoprotein reportedly functions as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD33
Applications Flow Cytometry
Classification Monoclonal
Clone WM53
Conjugate R718
Host Species Mouse
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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