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  6. Invitrogen™ CD335 (NKp46) Monoclonal Antibody (29A1.4), Brilliant Violet™ 711, eBioscience™, Invitrogen™ 

Invitrogen™ CD335 (NKp46) Monoclonal Antibody (29A1.4), Brilliant Violet™ 711, eBioscience™, Invitrogen™
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Catalog No. 407335182
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40-733-5182 100 μg
40-733-5180 25 μg
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Catalog No. 40-733-5182 Supplier Invitrogen™ Supplier No. 407335182
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Description

Rat Monoclonal Antibody

CD335, also known as NKp46 or NCR1, is a member of the natural cytotoxicity receptor family, which includes NKp30 and NKp44. This type I transmembrane glycoprotein is expressed on NK cells and plays a crucial role in activating and expanding resting NK cells through interactions with dendritic cells. CD335 enhances the ability of NK cells to eliminate tumor and virus-infected cells, such as those infected by influenza. CD335 consists of two Ig-like domains and is related to leukocyte immunoglobulin-like receptors (LIR) and killer inhibitory receptors (KIR). It contributes to the increased efficiency of activated NK cells in mediating tumor cell lysis. Additionally, CD335 interacts with pancreatic beta cells during the development of type 1 diabetes, highlighting its involvement in both immune defense and autoimmune processes.
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Specifications

Antigen CD335 (NKp46)
Applications Flow Cytometry
Classification Monoclonal
Clone 29A1.4
Concentration 0.2 mg/mL
Conjugate Brilliant Violet 711
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene NCR1
Gene Accession No. Q8C567
Gene Alias 1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1
Gene Symbols NCR1
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17086
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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