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  6. Invitrogen™ CD335 (NKp46) Monoclonal Antibody (9E2), NovaFluor™ Blue 610-70S, eBioscience™, Invitrogen™ 

Invitrogen™ CD335 (NKp46) Monoclonal Antibody (9E2), NovaFluor™ Blue 610-70S, eBioscience™, Invitrogen™

Catalog No. H040T02B06A
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H040T02B06A 25 Tests
H040T03B06A 100 Tests
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Catalog No. H040T02B06A Supplier Invitrogen™ Supplier No. H040T02B06A
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Description

Mouse Monoclonal Antibody

CD335, also known as NKp46 or NCR1, is a member of the natural cytotoxicity receptor family, which includes NKp30 and NKp44. This type I transmembrane glycoprotein is expressed on NK cells and plays a crucial role in activating and expanding resting NK cells through interactions with dendritic cells. CD335 enhances the ability of NK cells to eliminate tumor and virus-infected cells, such as those infected by influenza. CD335 consists of two Ig-like domains and is related to leukocyte immunoglobulin-like receptors (LIR) and killer inhibitory receptors (KIR). It contributes to the increased efficiency of activated NK cells in mediating tumor cell lysis. Additionally, CD335 interacts with pancreatic beta cells during the development of type 1 diabetes, highlighting its involvement in both immune defense and autoimmune processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD335 (NKp46)
Applications Flow Cytometry
Classification Monoclonal
Clone 9E2
Concentration 0.8 μg/Test
Conjugate NovaFluor Blue 610-70S
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene NCR1
Gene Accession No. O76036
Gene Alias 1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1
Gene Symbols NCR1
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9437
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG1 κ
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