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Invitrogen™ CD336 (NKp44) Polyclonal Antibody

Catalog No. PIPA5122115
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200 μL
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PIPA5122115 20 μL
PIPA5119302 200 μL
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Catalog No. PIPA5122115 Supplier Invitrogen™ Supplier No. PA5122115
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Description

Rabbit Polyclonal Antibody

CD336 (NKp44) Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD336 (NKp44)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene NCR2
Gene Accession No. O95944
Gene Alias CD336; CD336 antigen; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44; NK-p44dJ149M18.1
Gene Symbols NCR2
Host Species Rabbit
Immunogen Recombinant protein Natural Cytotoxicity Triggering Receptor 2. The antigen corresponds to amino acid range 22-120 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 367216, 9436
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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