CD336 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5996	150 μL

Catalog No. 50-173-5996 Supplier Proteintech Group Inc Supplier No. 551181AP150UL

Description

Rabbit Polyclonal Antibody

The antibody is specific to CD336.

CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.

Specifications

• Antigen: CD336
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.31 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NCR2
• Gene Accession No.: O95944
• Gene Alias: CD336, LY95, Lymphocyte antigen 95 homolog, NCR2, NK cell activating receptor, NK p44, NKP44
• Gene Symbols: NCR2
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9436
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG