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CD34 Antibody (ICO-115), PE/Cy7, Novus Biologicals™
SDP

Catalog No. N233076PEC7 Shop All R&D Systems Products
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N233076PEC7 0.1 mL
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Catalog No. N233076PEC7 Supplier Novus Biologicals Supplier No. NBP233076PECY7
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Description

Mouse Monoclonal Antibody

CD34 Monoclonal specifically detects CD34 in Human, Rat samples. It is validated for Flow Cytometry.

Specifications

Antigen CD34
Applications Flow Cytometry
Classification Monoclonal
Clone ICO-115
Conjugate PE-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Gene Symbols CD34
Host Species Mouse
Immunogen Blast cells from a chronic myeloid leukemia patient were used as the immunogen for the CD34 antibody.
Purification Method Protein G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 947.0
Test Specificity This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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