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CD344 Mouse, anti-Human, R718, Clone: CH3A4A7, BD OptiBuild™

Catalog No. BDB752194 Shop All BD Biosciences Products
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BDB752194 50 μg
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Catalog No. BDB752194 Supplier BD Biosciences Supplier No. 752194
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Description

Mouse Monoclonal Antibody

The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD344
Applications Flow Cytometry
Classification Monoclonal
Clone CH3A4A7
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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