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CD35 Antibody (CR1/802), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP24786A94 Shop All R&D Systems Products
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NP24786A94 0.1 mL
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Catalog No. NP24786A94 Supplier Novus Biologicals Supplier No. NBP247865AF594
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Description

Mouse Monoclonal Antibody

CD35 Monoclonal specifically detects CD35 in Human, Monkey, Baboon samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen CD35
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone CR1/802
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias complement component (3b/4b) receptor 1 (Knops blood group), KN
Gene Symbols CR1
Host Species Mouse
Immunogen Recombinant full-length human CD35 protein (Uniprot: P17927)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1378
Test Specificity Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.
Target Species Human, Monkey, Baboon
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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