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CD35 Antibody (CR1/802), Novus Biologicals™
SDP

Catalog No. p-5539521 Shop All R&D Systems Products
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NBP24461900 0.02 mg
NBP24461901 0.1 mg
NBP24461902 0.2 mg
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Catalog No. NBP24461900 Supplier Novus Biologicals Supplier No. NBP2446190.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CD35 Monoclonal specifically detects CD35 in Human, Baboon, Monkey samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen CD35
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone CR1/802
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P17927
Gene Alias complement component (3b/4b) receptor 1 (Knops blood group), KN
Gene Symbols CR1
Host Species Mouse
Immunogen Recombinant human CR1 protein
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1378
Test Specificity Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Target Species Human, Baboon, Monkey
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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