CD35 Mouse, Clone: SPM554, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP232821F	Novus Biologicals NBP2328210.02MG	0.02 mg
NBP232821A	Novus Biologicals NBP2328210.1MG	0.1 mg
NBP232821B	Novus Biologicals NBP2328210.2MG	0.2 mg

Description

CD35 Monoclonal specifically detects CD35 in Human, Chimpanzee, Baboon, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: CD35
• Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: complement component (3b/4b) receptor 1 (Knops blood group), KN
• Gene Symbols: CR1
• Isotype: IgG1 κ
• Purification Method: Protein A purified
• Test Specificity: Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

• Clone: SPM554
• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Baboon, Primate
• Gene Accession No.: P17927
• Gene ID (Entrez): 1378
• Immunogen: Intact human monocytes
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.