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Invitrogen™ CD354 (TREM-1) Monoclonal Antibody (L5-B8.2A12.3A12), PE
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Catalog No. PIMA528221
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Quantity:
100 Tests
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Catalog No. Quantity
PIMA528221 100 Tests
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Catalog No. PIMA528221 Supplier Invitrogen™ Supplier No. MA528221
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Description

Rat Monoclonal Antibody

Reconstitute with 1.0 mL distilled water Rat anti Mouse Trem-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes.

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
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Specifications

Antigen CD354 (TREM-1)
Applications Flow Cytometry
Classification Monoclonal
Clone L5-B8.2A12.3A12
Concentration Conc. Not Determined
Conjugate PE
Formulation PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene TREM1
Gene Accession No. Q9JKE2
Gene Alias CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Gene Symbols TREM1
Host Species Rat
Immunogen Mouse TREM-1 Fc fusion protein.
Purification Method Protein G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58217
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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