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Invitrogen™ CD357 (AITR/GITR) Chimeric Recombinant Rabbit Monoclonal Antibody (YGITR765)
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Catalog No. PIMA548021
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Quantity:
200 μg
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Catalog No. Quantity
PIMA548021 200 μg
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Catalog No. PIMA548021 Supplier Invitrogen™ Supplier No. MA548021
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody binds murine GITR.

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD357 (AITR/GITR) Chimeric
Applications Flow Cytometry, Inhibition Assays, Immunocytochemistry
Classification Recombinant Monoclonal
Clone YGITR765
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Tnfrsf18
Gene Accession No. O35714
Gene Alias Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Gene Symbols Tnfrsf18
Host Species Rabbit
Immunogen nB2/6TG cells transfected with mouse GITR injected into DA rats.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21936
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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