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  6. Invitrogen™ CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), APC-eFluor™ 780, eBioscience™, Invitrogen™ 

Invitrogen™ CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), APC-eFluor™ 780, eBioscience™, Invitrogen™

Catalog No. 47587541
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25 Tests
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Catalog No. Quantity
47-587-541 25 Tests
47-587-542 100 Tests
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Catalog No. 47-587-541 Supplier Invitrogen™ Supplier No. 47587541

Description

Mouse Monoclonal Antibody

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD357 (AITR/GITR)
Applications Flow Cytometry
Classification Monoclonal
Clone eBioAITR
Concentration 5 μL/Test
Conjugate APC-eFluor 780
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Tnfrsf18
Gene Accession No. Q9Y5U5
Gene Alias Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Gene Symbols Tnfrsf18
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8784
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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