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CD368 (Clec6) Monoclonal Antibody (9B9), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$186.00 - $453.00
Specifications
| Antigen | CD368 (Clec6) |
|---|---|
| Clone | 9B9 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-911-341
|
Invitrogen™
50911341 |
25 Tests |
Each for $186.00
|
|
|||||
|
50-911-342
|
Invitrogen™
50911342 |
100 Tests |
Each for $453.00
|
|
|||||
Description
This 9B9 MAb reacts with human CD368, also known as Clec6 or ClecsF8 or Clec4D. In peripheral blood, this C-type lectin is expressed highly on granulocytes and CD14+CD16- monocytes. Some dendritic cell populations also exhibit low levels of CD368 expression. Studies have demonstrated that this receptor undergoes endocytosis due to its C-type lectin-like domain. CD368 functions as a phagocytic receptor and is involved in proinflammatory cytokine production in cooperation with Toll-like receptors. Finally, CD368 also participates in cellular activation via signaling through Syk kinase.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.Specifications
| CD368 (Clec6) | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| CD368; Clec4d; CLEC6; CLEC-6; CLECSF8; CLECSF8Mpcl; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8; C-type lectin domain family 4 member D; C-type lectin domain family 4, member d; C-type lectin receptor; C-type lectin superfamily member 8; C-type lectin, superfamily member 8; C-type lectin-like receptor 6; macrophage C-type lectin; macrophage-restricted C-type lectin; Mcl; MGC40078; Mpcl; superfamilymember 8 | |
| CLEC4D | |
| Primary | |
| 4°C, store in dark, DO NOT FREEZE! | |
| CLEC4D |
| 9B9 | |
| Flow Cytometry | |
| eFluor 660 | |
| Mouse | |
| Human | |
| Q8WXI8 | |
| 338339 | |
| IgG2b κ | |
| Affinity chromatography | |
| Antibody |
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