CD370 (CLEC9A/DNGR1) Monoclonal Antibody (1F6), Functional Grade, In Vivo PLATINUM™, Leinco Technologies™

Catalog No.	Quantity
50-254-4147	100 mg

Catalog No. 50-254-4147 Supplier Leinco Technologies Inc Supplier No. I2020100MG

Description

Mouse Monoclonal Antibody

Specificity: This clone 1F6 monoclonal antibody recognizes a direct epitope on mouse DNGR1/CLEC9A for CD8 positive dendritic cells, which can be exploited for tumor therapy, whilst also recognizing necrotic cells. This antibody can recognize both the short and long isoform of DNGR-1, which varies in a segment of the stalk region. Endotoxin Level: ≤ 0.5 EU/mg as determined by the LAL method. Purity: ≥95% monomer by analytical SEC and >95% by SDS Page. Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.

CD370 (CLEC9A/DNGR1) Monoclonal antibody specifically detects CD370 (CLEC9A/DNGR1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot

Specifications

• Antigen: CD370 (CLEC9A/DNGR1)
• Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
• Classification: Monoclonal
• Clone: 1F6
• Concentration: ≥5.0 mg/mL
• Conjugate: Functional Grade
• Formulation: PBS with no preservative; pH 7.2-7.4
• Gene: CLEC9A
• Gene Accession No.: Q8BRU4
• Gene Alias: 9830005G06Rik; CD370; Clec9a; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; DNGR-1; HEEE9341; RGD1562513; UNQ9341; UNQ9341/PRO34046
• Host Species: Mouse
• Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
• Purification Method: Protein A/G
• Quantity: 100 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 232414
• Target Species: Mouse
• Content And Storage: 4°C short term, -80°C long term
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1