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Invitrogen™ CD39 Recombinant Rabbit Monoclonal Antibody (12D12)
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Catalog No. FEMA549993
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100 μL
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FEMA549993 100 μL
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Catalog No. FEMA549993 Supplier Invitrogen™ Supplier No. MA549993
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Description

Rabbit Recombinant Monoclonal Antibody

CD39 Recombinant Monoclonal Antibody for Flow, ELISA

CD39 is an integral membrane protein characterized by two transmembrane domains and forms a homotetramer structure. It is recognized as the most prominent ectoenzyme within the immune system, primarily functioning to remove toxic extracellular ATP by converting it into ADP or AMP. CD39 works in conjunction with CD73 to hydrolyze ATP and is well characterized on Langerhans cells. Originally identified on activated lymphocytes, CD39 is expressed on a variety of immune cells, including peripheral blood B cells, monocytes, and T cell clones. It is also found on a subset of T cells, B cells, and dendritic cells, with weaker expression observed on monocytes and granulocytes. The CD39 cell surface antigen is a 70-100kD molecule, and its expression is induced on T cells and increases on B cells as a late activation antigen. CD39 possesses intrinsic ecto-ATPase activity, playing a crucial role in modulating extracellular nucleotide levels and contributing to immune regulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD39
Applications ELISA, Flow Cytometry
Classification Recombinant Monoclonal
Clone 12D12
Concentration 0.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ENTPD1
Gene Accession No. P49961
Gene Alias 2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Gene Symbols ENTPD1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ENTPD1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 953
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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