CD3D Mouse anti-Human, Clone:1F6A8, Abnova™

Mouse monoclonal antibody raised against recombinant human CD3D.

Supplier:  Abnova Corporation MAB17643

Catalog No. 89-333-945

Description

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq]

Specifications

• Antigen: CD3D
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Gene: CD3D
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 1F6A8
• Description: CD3d molecule, delta (CD3-TCR complex)
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: CD3-DELTA, T3D
• Immunogen: Recombinant protein corresponding to amino acid 22-105 of human CD3D from E. coli.
• Gene ID (Entrez): 915
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid