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Invitrogen™ CD3d Polyclonal Antibody
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Catalog No. PIPA528313
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100 μL
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PIPA528313 100 μL
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Catalog No. PIPA528313 Supplier Invitrogen™ Supplier No. PA528313
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat membrane. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3d
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Cd3d
Gene Accession No. P04234
Gene Alias CD3 antigen delta polypeptide; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 delta; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3D; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; IMD19; OKT3, delta chain; T3D; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain
Gene Symbols Cd3d
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CD3 delta. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 915
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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