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  6. BD Horizon™ CD4 Mouse, anti-Human, RY586, Clone: SK3, BD Horizon™

BD Horizon™ CD4 Mouse, anti-Human, RY586, Clone: SK3, BD Horizon™

Catalog No. BDB568098 Shop All BD Biosciences Products
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BDB568098 100 Tests
BDB568099 25 Tests
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Catalog No. BDB568098 Supplier BD Horizon™ Supplier No. 568098
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Description

Mouse Monoclonal Antibody

The SK3 monoclonal antibody specifically binds to CD4. The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is expressed on T-helper/inducer lymphocytes and monocytes. CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes. CD4 is also expressed on 80% to 95% of normal thymocytes. The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+). CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD4
Applications Flow Cytometry
Clone SK3
Conjugate RY586
Host Species Mouse
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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