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CD4 Recombinant Rabbit Monoclonal Antibody (BL-155-1C11), Bethyl Laboratories

Catalog No. 501571284
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50-157-1284 10 μL
50-157-1283 100 μL
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Catalog No. 50-157-1284 Supplier Bethyl Laboratories, Inc Supplier No. A700015T
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Description

Rabbit Recombit Monoclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Specifications

Antigen CD4
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone BL-155-1C11
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene CD4
Gene Accession No. P01730
Gene Alias CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Gene Symbols CD4
Host Species Rabbit
Immunogen Recombit protein representing the extracellular domain of human CD4
Purification Method Purified
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 920
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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