Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. BDB752085

CD4 v4 Mouse, anti-Human, R718, Clone: L120, BD OptiBuild™

Catalog No. BDB752085 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB752085 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. BDB752085 Supplier BD Biosciences Supplier No. 752085
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

The L120 monoclonal antibody specifically recognizes CD4. CD4 is an ∼59 kDa type I transmembrane glycoprotein that belongs to the Ig gene superfamily. CD4 is expressed on helper-inducer subset of T lymphocytes and monocytes. The CD4 antigen is involved in the Major Histocompatibility Complex (MHC) class II-restricted recognition of foreign antigens and has been identified as a receptor for HIV. The L120 antibody recognizes amino acids 306-370 of the antigen and does not block the binding of the gp120 of HIV, but inhibits the proliferation of CD4 T lymphocytes to MHC class II antigens. The CD4 antigen is present on most thymocytes, approximately 40% of peripheral blood lymphocytes, and at lower density on monocytes. Peripheral blood CD4+ T lymphocytes are lost over time during HIV infection, and this loss is correlated with disease progression.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD4 v4
Applications Flow Cytometry
Classification Monoclonal
Clone L120
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.