Invitrogen™ CD41/CD61 Monoclonal Antibody (PAC-1), Alexa Fluor™ 488

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544123

Catalog No. PIMA544123

Description

This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.

Specifications

• Antigen: CD41/CD61
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Gene: ITGA2B
• Gene Alias: alphaIIb protein; antigen CD61; BDPLT16; BDPLT2; CD41; CD41B; CD61; glycoprotein GPIIb; glycoprotein GPIIIa; glycoprotein IIb; glycoprotein IIIa; GP2B; GP3A; GPalpha IIb; GPIIb; GPIIIa; GT; GTA; HPA3; INTB3; integrin; integrin alpha 2b; integrin alpha 2b precursor; Integrin alpha-2b; integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; Integrin beta; integrin beta 3; integrin beta 3 subunit; integrin beta3; integrin beta-3; integrin beta-3 subunit; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin subunit beta 3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGA2B; ITGA2B-like protein; ITGAB; ITGB3; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/IIIa complex; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
• Host Species: Mouse
• Purification Method: Size-exclusion Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3674, 3690
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: PAC-1
• Formulation: TBS with 0.2% BSA and 15mM sodium azide
• Gene Accession No.: P05106, P08514
• Gene Symbols: ITGA2B, ITGB3
• Immunogen: Human platelets.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM κ