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CD41/Integrin alpha 2b Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen CD41/Integrin alpha 2b
Concentration 0.17 mg/mL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-2105
SDP
Encompass_Preferred
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Proteintech Group Inc
183081AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41/Integrin alpha 2b
Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse, Rat
P08514, Q9QUM0
16399, 3674, 685269
Peptide
Primary
-20°C
ITGA2B
0.17 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
Itga2b
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
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Documents

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