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Description
The MWReg30 antibody reacts with glycoprotein (gp) IIb, also called integrin αIIb chain (CD41), that associates with integrin β3 chain (gpIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.
Specifications
Specifications
| Antigen | CD41 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MWREG30 |
| Concentration | 0.5mg/mL |
| Conjugate | FITC |
| Description | Integrin α IIb chain |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Platelets |
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For Research Use Only.
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