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CD42b Mouse, anti-Human, R718, Clone: HIP1, BD OptiBuild™

Catalog No. BDB752125 Shop All BD Biosciences Products
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BDB752125 50 μg
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Catalog No. BDB752125 Supplier BD Biosciences Supplier No. 752125
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Description

Mouse Monoclonal Antibody

The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD42b
Applications Flow Cytometry
Classification Monoclonal
Clone HIP1
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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