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CD42d Mouse, anti-Rat, R718, Clone: RPM.4, BD OptiBuild™

Catalog No. BDB751986 Shop All BD Biosciences Products
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BDB751986 50 μg
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Catalog No. BDB751986 Supplier BD Biosciences Supplier No. 751986
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Description

Mouse Monoclonal Antibody

The RPM.4 monoclonal antibody specifically recognizes CD42d (Platelet glycoprotein V, GPV). CD42d is a 88-kDa type I transmembrane glycoprotein which noncovalently associates with GPIb and GPIX to form a receptor for von Willebrand factor on megakaryocytes and resting platelets. The binding sites for von Willebrand factor and thrombin have been localized to the GPIbα chain of the GPI-b-V-IX complex. GPV is cleaved by thrombin to release a 70 kDa soluble fragment, which contains the epitope recognized by mAb RPM.4. Although the rat CD42d protein's structure is similar to that of human CD42d, the RPM.4 antibody does not cross-react with human platelets.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD42d
Applications Flow Cytometry
Classification Monoclonal
Clone RPM.4
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Refrigerate Upon Arrival
Form Liquid
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