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CD43 Mouse, anti-Human, R718, Clone: L60, BD OptiBuild™

Catalog No. BDB752087 Shop All BD Biosciences Products
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BDB752087 50 μg
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Catalog No. BDB752087 Supplier BD Biosciences Supplier No. 752087
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Description

Mouse Monoclonal Antibody

The L60 monoclonal antibody specifically binds to CD43 which is also known as Leukosialin (LSN) or Galactoglycoprotein (GALGP). CD43 is a ∼95-135 kDa heavily O-sialylated type I transmembrane glycoprotein that is encoded by SPN (sialophorin) and belongs to the cell surface mucin family. The L60 antibody recognizes a sialic acid-dependent determinant on CD43. CD43 is highly expressed on T lymphocytes, thymocytes, monocytes, granulocytes, bone marrow stem cells, pre-B cells and activated B cells plasma cells but not on resting peripheral blood B cells, red blood cells, and non-hematopoietic cells. CD43 is enzymatically shed from leucocyte surfaces following activation by various stimuli. CD43 appears to be involved in mediating intercellular interactions that regulate leucocyte functions.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD43
Applications Flow Cytometry
Classification Monoclonal
Clone L60
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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