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CD43 Rat anti-Mouse, FITC, Clone: S7, BD

Catalog No. BDB553270 Shop All BD Biosciences Products
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BDB553270 0.5 mg
BDB561856 0.1 mg
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Catalog No. BDB553270 Supplier BD Biosciences Supplier No. 553270
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Description

Rat Monoclonal Antibody

The S7 monoclonal antibody specifically binds to the 115 kDa glycosylated form of CD43 (Ly-48, Leukosialin). CD43 is expressed on IL-7-responsive pro-B cells, plasma cells, peritoneal and splenic CD5+ B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, natural killer cells, thymocytes, peripheral T cytotoxic/suppressor cells, and most T helper cells, but not resting conventional peripheral B cells. CD43 expression has also been detected on pluripotent hematopoietic stem cells and myeloid, lymphoid, and NK-cell progenitors in the bone marrow. Studies of CD43-deficient mice indicate that CD43 participates in the negative regulation of T-cell activation and adhesion.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD43
Applications Flow Cytometry
Classification Monoclonal
Clone S7
Concentration 0.5mg/mL
Conjugate FITC
Description Spn ; Sialophorin; Leukosialin; Ly-48; Ly48; Galgp; LEUK
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse Plasmacytoma MOPC-315
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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