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CD44 Mouse anti-Human, Brilliant Violet 786, Clone: 515, BD Optibuild™

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BDB744272 50 μg
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Catalog No. BDB744272 Supplier BD Biosciences Supplier No. 744272
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Description

Mouse Monoclonal Antibody

The 515 monoclonal antibody specifically binds to CD44. CD44 is an 80-95 kDa type I transmembrane glycoprotein, also known as Phagocytic glycoprotein-1 (Pgp-1), or Extracellular matrix receptor type III (ECMR-III). CD44 is a member of the hyaladherin family of hyaluronan-binding proteins, with structural similarities to selectins. CD44 is the receptor for hyaluronic acid. CD44 is expressed on leucocytes, erythrocytes, epithelial cells and weakly on platelets. CD44 is also called and has functional roles in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation. The 515 monoclonal antibody can reportedly block cellular adhesion to hyaluronic acid.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter). BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm. BV786 offers a bright choice for the 6th detector off the violet laser.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD44
Classification Monoclonal
Clone 515
Concentration 0.2mg/mL
Conjugate Brilliant Violet 786
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Pgp-1, CSPG8, ECMR-III, Epican, H-CAM, HCELL, Hermes, HUTCH-1
Host Species Mouse
Immunogen Human EBV-transformed Arent B Lymphoblastoid Cell Line
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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