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  6. CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, Epredia™

CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS668P1 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Conjugate Form Concentration
MS668P1 500 μL Unconjugated Concentrated 200μg/mL
MS668P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS668P 1 mL Unconjugated Concentrated 200μg/mL
MS668B0 100 μL Biotin Concentrated 200μg/mL
MS668B1 500 μL Biotin Concentrated 200μg/mL
MS668B 1 mL Biotin Concentrated 200μg/mL
MS668PABX 200 μL Unconjugated Concentrated 1mg/mL
MS668R1 1 mL Unconjugated Prediluted Prediluted
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Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunoprecipitation and flow cytometry experiments.

CD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (H-CAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis. Ab-4 reacts with red cells pretreated with 2-aminoethylisothiouronium bromide (AET). Digestion of intact erythrocytes by trypsin treatment leaves a 50-54 kDa protein fragment attached to the membrane, while chymotrypsin leaves a somewhat similarly sized 51-56 kDa component that are recognized by Ab-4. This antibody enhances IL-2 production by CD2-transfected murine hybridoma stimulated by JY cells while it has no significant effect on IL-2 production by Jurkat cells stimulated with CD3, PMA, or CD2. Ab-4 enhances proliferation of PBL stimulated with CD2.

Host Species: Mouse

Clone: 156-3C11

Isotype: IgG2a

Species Reactivity: Human, Baboon and Green Monkey. Does not react with rat. Others not tested.

Epitope: Resistant to digestion by trypsin and chymotrypsin

Immunogen: Stimulated human leukocytes

Molecular Weight: 80-95 kDa

Positive Control: HUVEC or HeLa cells, tonsil or esophageal CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Flow Cytometry

Specifications

Antigen CD44 Std./H-CAM Ab-4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 156-3C11
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Stimulated human leukocytes
Quantity 500 μL
Regulatory Status IVD
Research Discipline Oncogenesis
Primary or Secondary Primary
Target Species Human, Non-human Primate
Form Concentrated
Isotype IgG2a
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