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CD44v4 Monoclonal Antibody (VFF-11), Invitrogen™

Catalog No. PIMA516962
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100 μg
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PIMA516962 100 μg
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Catalog No. PIMA516962 Supplier Thermo Scientific Supplier No. MA516962

Description

Mouse Monoclonal Antibody

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD44v4
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone VFF-11
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.01% thimerosal
Gene CD44
Gene Accession No. P16070
Gene Alias AL133330.1; AU023126; AW121933; AW146109; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 var; CD44 variant; CD44v4; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; H-CAM v4; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; MIC4; PGP I; Pgp1; PGP-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; RP23-203N8.3; soluble CD44
Gene Symbols CD44
Host Species Mouse
Immunogen Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44.
Purification Method purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 960
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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