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CD45 Mouse anti-Rat, FITC, Clone: OX-1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 554877

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Catalog No. BDB554877


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Description

Description

The OX-1 antibody reacts with all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD45
Monoclonal
0.5mg/mL
Ptprc; Lca; Leucocyte common antigen; RT7; T200
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
OX-1
FITC
Aqueous buffered solution containing ≤0.09% sodium azide.
Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
0.5 mg
Immunology
Rat
IgG1 κ
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