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CD45RA Mouse anti-Rat, FITC, Clone: OX-33, BD

Catalog No. BDB561886 Shop All BD Biosciences Products
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50 μg
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BDB561886 50 μg
BDB554883 0.5 mg
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Catalog No. BDB561886 Supplier BD Biosciences Supplier No. 561886
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Description

Mouse Monoclonal Antibody

The OX-33 antibody reacts with a high-molecular-weight form of CD45 found only on B lymphocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

This antibody isroutinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45RA
Applications Flow Cytometry
Classification Monoclonal
Clone OX-33
Concentration 0.5mg/mL
Conjugate FITC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Leukocyte common antigen purified from rat splenocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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