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Invitrogen™ CD45RC Monoclonal Antibody (C455.1F), FITC

Rat Monoclonal Antibody

Supplier:  Invitrogen™ RMCD45RC01

Encompass_Preferred

Catalog No. 50-113-8197


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Description

Description

CD45RC Monoclonal Antibody for Flow

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD45RC
Monoclonal
0.5 mg/mL
PBS with <0.1% sodium azide; pH 7.4
P06800
Ptprc
Mouse CD45RC.
500 μg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry
C455.1F
FITC
Ptprc
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Rat
Purified
RUO
19264
4°C, store in dark
Liquid
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