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Invitrogen™ CD45RC Monoclonal Antibody (C455.1F), FITC
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Catalog No. 501138197
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500 μg
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Catalog No. Quantity
50-113-8197 500 μg
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Catalog No. 50-113-8197 Supplier Invitrogen™ Supplier No. RMCD45RC01
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Description

Rat Monoclonal Antibody

CD45RC Monoclonal Antibody for Flow

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45RC
Applications Flow Cytometry
Classification Monoclonal
Clone C455.1F
Concentration 0.5 mg/mL
Conjugate FITC
Formulation PBS with <0.1% sodium azide; pH 7.4
Gene Ptprc
Gene Accession No. P06800
Gene Alias B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols Ptprc
Host Species Rat
Immunogen Mouse CD45RC.
Purification Method Purified
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19264
Target Species Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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