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Invitrogen™ CD45RC Monoclonal Antibody (OX-22), PE
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Catalog No. PIMA517462
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50 μg
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PIMA517462 50 μg
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Catalog No. PIMA517462 Supplier Invitrogen™ Supplier No. MA517462
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Description

Mouse Monoclonal Antibody

MA5-17462 targets CD45RC in FACS applications and shows reactivity with Rat samples. The MA5-17462 immunogen is phytohaemagglutinin-activated rat lymph node cells.

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45RC
Applications Flow Cytometry
Classification Monoclonal
Clone OX-22
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene Ptprc
Gene Accession No. P04157
Gene Alias B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols Ptprc
Host Species Mouse
Immunogen Phytohaemagglutinin-activated rat lymph node cells.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24699
Target Species Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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