CD45RO Mouse anti-Human, PE, Clone: UCHL1, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561889	BD Biosciences 561889	25 Tests
BDB555493	BD Biosciences 555493	100 Tests

Description

The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen). CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways. This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.

Specifications

• Antigen: CD45RO
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgG2a κ
• Purification Method: Affinity Purified

• Clone: UCHL1
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human IL-2-dependent T-cell line
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.