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CD46/MCP Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983649
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50-198-3649 100 μL
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Catalog No. 50-198-3649 Supplier Bioss Supplier No. BS1529R
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Description

Rabbit Polyclonal Antibody

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Specifications

Antigen CD46/MCP
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CD46
Gene Accession No. P15529
Gene Alias AHUS2; antigen identified by monoclonal antibody TRA-2-10; BOS_16108; brain microvascular membrane cofactor; CD46; CD46 antigen, complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; complement membrane cofactor protein; MCP; measles virus receptor; Membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MGC26544; MIC10; TLX; TRA2.10; trophoblast leucocyte common antigen; Trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen
Gene Symbols CD46
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from Mouse CD46 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4179
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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