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Invitrogen™ CD49a Monoclonal Antibody (CL7207)
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Catalog No. PIMA535041
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100 μL
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Catalog No. Quantity
PIMA535041 100 μL
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Catalog No. PIMA535041 Supplier Invitrogen™ Supplier No. MA535041
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Description

Mouse Monoclonal Antibody

Immunogen sequence: RQISRSFFSG TQERKVQRN Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 89%.

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49a
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL7207
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Itga1
Gene Accession No. P56199
Gene Alias CD49 antigen-like family member A; CD49a; E130012M19Rik; integrin alpha 1; integrin alpha-1; integrin subunit alpha 1; integrin, alpha 1; Itga1; Laminin and collagen receptor; very late activation protein 1; Vla1; VLA-1
Gene Symbols Itga1
Host Species Mouse
Immunogen Synthetic Peptide corresponding to Human CD49a.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3672
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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