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CD49a Mouse anti-Human, BUV395, Clone: SR84, BD Optibuild™

Catalog No. BDB742363 Shop All BD Biosciences Products
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BDB742363 50 μg
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Catalog No. BDB742363 Supplier BD Biosciences Supplier No. 742363
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Description

Mouse Monoclonal Antibody

The SR84 monoclonal antibody specifically recognizes CD49a (CD49 antigen-like family member A). CD49a is a ñ200 kDa type I transmembrane molecule that is encoded by ITGA1 ( /Integrin subunit alpha 1). CD49a is also known as very late antigen 1αsubunit (VLA-1) of the integrin family of cell adhesion molecules. CD49a associates with the integrinβ1 subunit (CD29) to form theα1/β1 heterodimer (CD49a/CD29), and serves as receptor for collagen and laminin-1. It is expressed on activated T cells, monocytes, neuronal cells and smooth muscle cells. CD49a has been reported to play a role in cell attachment during the development of both the central and peripheral nervous systems.

The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry. With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter. BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences. With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter. This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49a
Classification Monoclonal
Clone SR84
Concentration 0.2mg/mL
Conjugate Brilliant Ultraviolet 395
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Integrin α1, Integrin alpha-1, ITGA1, ITA1, VLA-1, VLA1
Host Species Mouse
Immunogen P-Selectin IgG1 Fusion
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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