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CD49c Mouse, anti-Human, R718, Clone: C3 II.1, BD OptiBuild™

Catalog No. BDB752217 Shop All BD Biosciences Products
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BDB752217 50 μg
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Catalog No. BDB752217 Supplier BD Biosciences Supplier No. 752217
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Description

Mouse Monoclonal Antibody

The C3 II.1 monoclonal antibody specifically recognizes CD49c which is also known as Integrin alpha 3 (α3 integrin). CD49c is encoded by ITGA3 (Integrin subunit alpha 3). CD49c is a 150 kDa type I transmembrane glycoprotein which non-covalently associates with integrin β1 (CD29) to form the α3β1 (CD49c/CD29, VLA-3) complex. CD49c is expressed mostly on endothelial and epithelial cells (basal epidermal layers). It is not expressed on platelets and is expressed weakly on peripheral blood leucocytes, including T cells, B cells, and monocytes. The CD49c/CD29 complex serves as an adhesive receptor for kalinin or epiligrin. This interaction may be important for thymocyte interaction with thymic epithelium.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49c
Applications Flow Cytometry
Classification Monoclonal
Clone C3 II.1
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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