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CD49d Mouse anti-Baboon, Equine, Feline, Human, Brilliant Ultraviolet 737, Clone: 9F10, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 612850

Catalog No. BDB612850


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Description

Description

The 9F10 monoclonal antibody specifically reacts with the integrin α 4 chain, that is expressed as a heterodimer with either of two β integrin subunits, β 1 (CD29) or β 7. The α 4β 1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The α β 7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express α 4 chain-containing integrins. This clone cross-reacts with a subset of peripheral blood lymphocytes, monocytes, and some granulocytes of baboon and both rhesus and cynomolgus macaque monkeys. The distribution on leukocytes is similar to that observed with human peripheral blood leukocytes.

Specifications

Specifications

CD49d
9F10
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse
Affinity Chromatography
RUO
Primary
Baboon, Equine, Feline, Human
Flow Cytometry
Brilliant Ultraviolet 737
Affinity Purified
IgG1, κ
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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