CD49d Mouse anti-Human, APC, Clone: 9F10, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561892	BD Biosciences 561892	25 Tests
BDB559881	BD Biosciences 559881	100 Tests

Description

The 9F10 monoclonal antibody specifically reacts with the integrin α4 chain, that is expressed as a heterodimer with either of two β integrin subunits, β1 (CD29) or β7. The α4β1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The αβ7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express α4 chain-containing integrins.

Specifications

• Antigen: CD49d
• Applications: Flow Cytometry
• Conjugate: APC
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: 9F10
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Baboon, Bovine, Canine, Cynomolgus, Equine, Feline, Human, Rhesus Monkey, Sheep
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4

For Research Use Only.