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  6. CD49d Mouse anti-Human, PE, Clone: 9F10, BD

CD49d Mouse anti-Human, PE, Clone: 9F10, BD

Catalog No. BDB556635 Shop All BD Biosciences Products
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Catalog No. BDB556635 Supplier BD Biosciences Supplier No. 556635

Description

Mouse Monoclonal Antibody

The 9F10 monoclonal antibody specifically reacts with the integrin α4 chain, that is expressed as a heterodimer with either of two β integrin subunits, β1 (CD29) or β7. The α4β1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The αβ7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express α4 chain-containing integrins.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49d
Applications Flow Cytometry
Classification Monoclonal
Clone 9F10
Conjugate PE
Description Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Baboon, Bovine, Canine, Cynomolgus, Equine, Feline, Human, Rhesus Monkey, Sheep
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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