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  6. Invitrogen™ CD49e (Integrin alpha 5) Monoclonal Antibody (eBioSAM-1 (SAM-1, SAM1)), eBioscience™, Invitrogen™ 

Invitrogen™ CD49e (Integrin alpha 5) Monoclonal Antibody (eBioSAM-1 (SAM-1, SAM1)), eBioscience™, Invitrogen™

Catalog No. 14049637
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14-049-637 2 mg
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Catalog No. 14-049-637 Supplier Invitrogen™ Supplier No. 14049637
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Description

Mouse Monoclonal Antibody

The eBioSAM-1 MAb reacts with human integrin alpha 5, also known as fibronectin receptor alpha chain, very late activation antigen 5 alpha, and CD49e. Integrins are composed of an alpha chain and a beta chain, which non-covalently associate to form the functional integrin. Integrin heterodimers participate in cell surface-mediated signaling and adhesion functions. Integrin alpha 5 undergoes post-translational cleavage in its extracellular domain to yield disulfide linked light and heavy chains that join with Integrin beta 1 (CD29) to form the fibronectin receptor, also known as the very late activation antigen-5 (VLA-5) complex. Integrin alpha 5 is expressed on thymocytes, T cells, monocytes, platelets, early B cells, and activated B cells.

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49e (Integrin alpha 5)
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification Monoclonal
Clone eBioSAM-1 (SAM-1, SAM1)
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Itga5
Gene Accession No. P08648
Gene Alias 2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; CD49 antigen-like family member E; Cd49e; C-myc promoter-binding protein; ENO1; ENO1L1; Enolase 1; enolase 1, (alpha); enolase-alpha; epididymis secretory protein Li 17; fibronectin receptor alpha polypeptide; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; HEL-S-17; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; integrin subunit alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Itga5_retired; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin; very late activation protein 5, alpha subunit; VLA5; VLA-5; VLA5A
Gene Symbols Itga5
Host Species Mouse
Purification Method Affinity chromatography
Quantity 2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3678
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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