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Invitrogen™ CD51/CD61 Monoclonal Antibody (23C6)
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Catalog No. PIMA133578
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100 μg
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PIMA133578 100 μg
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Catalog No. PIMA133578 Supplier Invitrogen™ Supplier No. MA133578
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Mouse Monoclonal Antibody

For flow cytometry use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD51/CD61
Applications Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Immunocytochemistry, Western Blot (Agglutination)
Classification Monoclonal
Clone 23C6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene ITGB3
Gene Accession No. P05106, P06756, P26008
Gene Alias 1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; INGRB3; integrin; integrin alpha V; integrin alpha-5 beta-3; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; Integrin beta; integrin beta 3; integrin beta 3 (Cd61); Integrin beta3; integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; platelet gpIIIa; platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor alpha subunit; vitronectin receptor subunit alpha; VNRA; VTNR
Gene Symbols ITGAV, ITGB3
Host Species Mouse
Immunogen Osteoclasts from osteoclastomas.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29302, 296456, 3685, 3690, 374209, 396420
Target Species Chicken, Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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