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Invitrogen™ CD51/CD61 Monoclonal Antibody (23C6)
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Catalog No. PIMA516470
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200 μg
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Catalog No. Quantity
PIMA516470 200 μg
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Catalog No. PIMA516470 Supplier Invitrogen™ Supplier No. MA516470
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Description

Mouse Monoclonal Antibody

This antibody does not react with bovine, pig or rabbit. The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommend the use of acetone fixation for frozen sections. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD51/CD61
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone 23C6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene ITGAV
Gene Accession No. P05106, P06756, P26008
Gene Alias 1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; INGRB3; integrin; integrin alpha V; integrin alpha-5 beta-3; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; Integrin beta; integrin beta 3; integrin beta 3 (Cd61); Integrin beta3; integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; platelet gpIIIa; platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor alpha subunit; vitronectin receptor subunit alpha; VNRA; VTNR
Gene Symbols ITGAV, ITGB3
Host Species Mouse
Immunogen Osteoclasts from osteoclastomas.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3685, 3690, 374209, 396420
Target Species Human, Chicken
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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