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CD51/CD61 Mouse, anti-Human, R718, Clone: 23C6, BD OptiBuild™

Catalog No. BDB752235 Shop All BD Biosciences Products
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BDB752235 50 μg
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Catalog No. BDB752235 Supplier BD Biosciences Supplier No. 752235
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Mouse Monoclonal Antibody

The 23C6 monoclonal antibody specifically binds to the Integrin αvβ3 heterodimeric complex (CD51/CD61) that is expressed on osteoclasts, endothelial cells, macrophages, melanoma cells, some B cells and in very low amounts on platelets. This antibody has been reported to crossreact with chicken, bovine, and rabbit, but not with rat αvβ3. The integrin αvβ3 heterodimer, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin including, von Willebrand factor, thrombospondin, osteopontin, bone sialoprotein, neural adhesion molecule L1, laminin, fibronectin, and fibrinogen. The binding of some ligands to the vitronectin receptor has been reported to be inhibited by the 23C6 monoclonal antibody.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD51/CD61
Applications Flow Cytometry
Classification Monoclonal
Clone 23C6
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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